CALL FOR PAPERS Intestinal Stem Cells in GI Physiology and Disease Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine

نویسندگان

  • Denise Al Alam
  • Soula Danopoulos
  • Kathy Schall
  • Frederic G. Sala
  • Dana Almohazey
  • G. Esteban Fernandez
  • Senta Georgia
  • Mark R. Frey
  • Henri R. Ford
  • Tracy Grikscheit
  • Saverio Bellusci
چکیده

Denise Al Alam, Soula Danopoulos, Kathy Schall, Frederic G. Sala, Dana Almohazey, G. Esteban Fernandez, Senta Georgia, Mark R. Frey, Henri R. Ford, Tracy Grikscheit,* and Saverio Bellusci* Keck School of Medicine, University of Southern California, Los Angeles, California; Developmental Biology and Regenerative Medicine Program, Saban Research Institute of Children’s Hospital Los Angeles, Los Angeles, California; Department of Internal Medicine II, University of Giessen Lung Center and Member of the German Lung Center, Giessen, Germany; and Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia

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Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine.

Intestinal epithelial cell renewal relies on the right balance of epithelial cell migration, proliferation, differentiation, and apoptosis. Intestinal epithelial cells consist of absorptive and secretory lineage. The latter is comprised of goblet, Paneth, and enteroendocrine cells. Fibroblast growth factor 10 (FGF10) plays a central role in epithelial cell proliferation, survival, and different...

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تاریخ انتشار 2015